- 2023 Nov 20;58(22):2495-2509.e6.
Publications
2023
PARP14 is a PARP with both ADP-ribosyl transferase and hydrolase activities. Sci Adv. 9(37):eadi2687
https://doi.org/10.1126/sciadv.adi2687
Viral subversion of selective autophagy is critical for biogenesis of virus replication organelles. Nat Commun 14(1):2698
https://doi.org/10.1038/s41467-023-38377-w
Updated protein domain annotation of the PARP protein family sheds new light on biological function Nucleic Acids Res 51(15):8217-8236
https://doi.org/10.1093/nar/gkad514
Usp25-Erlin1/2 activity limits cholesterol flux to restrict virus infection. Dev Cell 58(22):2495-2509.e6
https://doi.org/10.1016/j.devcel.2023.08.013
Crossroads in virology: current challenges and future perspectives in the age of emerging viruses. Dis Model Mech 16(10):dmm050476.
https://doi.org/10.1242/dmm.050476
Amino acid substitution L232F in non-structural protein 6 identified as a possible human-adaptive mutation in clade B MERS coronaviruses. J Virol 97(12): e0136923
https://doi.org/10.1128/jvi.01369-23
2022
ISG15 driven cellular responses to virus infection. Biochem Soc Trans 50(6): 1837-1846 (2022).
https://doi.org/10.1042/BST20220839
2021
Munnur, D., Teo, Q., Eggermont, D. et al. Altered ISGylation drives aberrant macrophage-dependent immune responses during SARS-CoV-2 infection. Nat Immunol 22, 1416–1427 (2021).
https://doi.org/10.1038/s41590-021-01035-8
Thery, F., Martina, L., Asselman, C. et al. Ring finger protein 213 assembles into a sensor for ISGylated proteins with antimicrobial activity. Nat Commun 12, 5772 (2021).
https://doi.org/10.1038/s41467-021-26061-w
Sophie Wilhelmina van Leur, Tiaan Heunis, Deeksha Munnur & Sumana Sanyal (2021) Pathogenesis and virulence of flavivirus infections, Virulence, 12:1, 2814-2838
https://doi.org/10.1080/21505594.2021.1996059
Teo, Q.W., van Leur, S.W. and Sanyal, S. (2021), Escaping the Lion’s Den: redirecting autophagy for unconventional release and spread of viruses. FEBS J, 288: 3913-3927.
https://doi.org/10.1111/febs.15590
2020
Sumana Sanyal; How SARS-CoV-2 (COVID-19) spreads within infected hosts — what we know so far. Emerg Top Life Sci 11 December 2020; 4 (4): 383–390.
https://doi.org/10.1042/ETLS20200165
Zhang J, Lan Y, Sanyal S. Membrane heist: Coronavirus host membrane remodeling during replication. Biochimie. 2020;179:229-236.
https://doi.org/10.1016/j.biochi.2020.10.010
Li, M.Y., Naik, T.S., Siu, L.Y.L. et al. Lyn kinase regulates egress of flaviviruses in autophagosome-derived organelles. Nat Commun 11, 5189 (2020).
https://doi.org/10.1038/s41467-020-19028-w
Wong HH, Sanyal S. Manipulation of autophagy by (+) RNA viruses. Seminars in Cell & Developmental Biology. 2020;101:3-11.
https://doi.org/10.1016/j.semcdb.2019.07.013
Jahan AS, Biquand E, Muñoz-Moreno R, Le Quang A, Mok CK-P, Wong HH, et al. OTUB1 Is a Key Regulator of RIG-I-Dependent Immune Signaling and Is Targeted for Proteasomal Degradation by Influenza A NS1. Cell Reports. 2020;30(5):1570-84.e6.
https://doi.org/10.1016/j.celrep.2020.01.015
2019
Fan Y, Sanyal S, Bruzzone R. Breaking Bad: How Viruses Subvert the Cell Cycle. Front Cell Infect Microbiol. 2018;8:396. Published 2018 Nov 19. https://doi.org/10.3389/fcimb.2018.00396
2018
Zhang J, Lan Y, Li MY, Lamers MM, Fusade-Boyer M, Klemm E, et al. Flaviviruses Exploit the Lipid Droplet Protein AUP1 to Trigger Lipophagy and Drive Virus Production. Cell Host & Microbe. 2018;23(6):819-31.e5.